THE SCIENCE OF LASER LEAD EXTRACTION OR REMOVAL
Light Amplification by Stimulated Emission of Radiation.
Photoablation is the use of ultraviolet laser light to break down and remove matter.
The Spectranetics CVX-300® Excimer Laser System generates 308 nanometers (nm) laser energy by electrically charging two gases, Xenon and Chloride (XeCl). The laser energy is transmitted along flexible fiber-optic strands encased in catheters and sheaths, which are passed through arteries and veins. The ultraviolet light energy is focused on the cardiovascular lesion or tissue requiring treatment. This process is called photoablation.
In peripheral vascular intervention, Spectranetics’ excimer laser system uses ultraviolet light to ablate blockages associated with peripheral arterial disease above and below-the-knee and to treat multiple morphology lesions comprising atheroma, fibrosis, calcium, and thrombus.
Laser light emitted from the Spectranetics laser is in the blue, or ultraviolet, spectrum at 308nm – similar to laser light employed for LASIK at ~193nm. As light moves toward the red spectrum it increases in temperature.
Mechanisms of Action: How Does Photoablation Work?
Excimer laser light is delivered to the tissue through a fiber-optic catheter. In a liquid environment, three mechanisms contribute to the ablation process: photochemical, photothermal and photomechanical. Transfer of the photothermal energy leads to vaporization.
1. PHOTOCHEMICAL: 2. PHOTOTHERMAL: , 3. PHOTOMECHANICAL:
Dissolving Molecular Bonds Produces Photothermal Energy Creating Kinetic Energy
1. Vaporizing Molecular Bonds
2. Producing Photothermal Energy
3. Creating Kinetic Energy
Timeline of a Single Pulse
PULSE RATE = NUMBER OF TIMES A LASER PULSES PER SECOND =HZ